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Contaminant · PFAS

HFPO-DA (GenX) in drinking water

CAS 13252-13-6 · EPA record reviewed 2026-09-02

Hexafluoropropylene oxide dimer acid, the main 'GenX' replacement chemical for PFOA, best known from the Cape Fear River basin.

In focus10,307Systems tested nationwide
Public records. Clearer context.
Highest result against its EPA referenceHFPO-DA (GenX), highest published-system value
HFPO-DA (GenX), highest published-system value: 81.4 ppt; MCL (rescission proposed) 10.0 ppt. highest complete sampling-location average.81.4 pptMCL (rescission proposed): 10.0 ppt

highest complete sampling-location average; sampled 2023–2025. Source: EPA records; Abbeville City of (Sc0110001) (SC0110001).

48
systems where it was found
of 10,307 tested
0.47%
of tested systems found it
170 ppt
highest single result in EPA's survey
10.0 ppt
EPA MCL (rescission proposed)
compared on the yearly average

What the rules say

The April 2024 PFAS rule set a 10 ng/L (ppt) limit for HFPO-DA (GenX chemicals). In May 2026 EPA proposed rescinding that limit. Until a final decision, the 10 ng/L figure is shown for reference only.

What EPA's assessment says

EPA's 2021 toxicity assessment for GenX chemicals cites liver, kidney, immune and developmental effects in animal studies.

Read the EPA source for HFPO-DA (GenX).

Across the country

EPA tested 10,307 water systems for HFPO-DA (GenX) and found it in 48. Half of the systems that found it measured less than 7.7 ppt, and one in ten measured more than 35.5 ppt.

EPA's final UCMR 5 occurrence file contains 66,362 HFPO-DA (GenX) results from 10,307 systems. 128 results were at or above the minimum reporting level, across 48 systems. Among detections, the median was 7.7 ppt and the 90th percentile was 35.5 ppt.

10 systems had a result at or above the reference on the page's stated comparison basis. For contaminants with a limit, that basis is the yearly average at the highest sampling location, not the highest single sample.

Systems with the highest recorded HFPO-DA (GenX) results

SystemStatePopulation servedRecorded valueRecords / periods
Abbeville City of (Sc0110001) SC0110001South Carolina5,65081.4 ppt4
Greenwood Cpw (2410001) SC2410001South Carolina52,02262.8 ppt4
Belton City of (Sc0410004) SC0410004South Carolina6,76241.9 ppt4
Laurens County W&s Comm (Sc3020001) SC3020001South Carolina44,86635.1 ppt5
Robeson County Water System NC0378055North Carolina67,97033.5 ppt2
Honea Path Town of (Sc0410003) SC0410003South Carolina4,38625.5 ppt8
Saluda Cpw (Sc4110001) SC4110001South Carolina3,39025.2 ppt3
Donalds-Due West W&SA (Sc0120001) SC0120001South Carolina5,20016.4 ppt8
Ware Shoals Town of (Sc2410003) SC2410003South Carolina3,17412.8 ppt4
Perth Amboy Water Department NJ1216001New Jersey52,32811.9 ppt4
Newberry City of (3610001) SC3610001South Carolina9,9478.7 ppt4
Bgwc I-20 (Sc3250012) SC3250012South Carolina7,1468.5 ppt4
Joint Municipal WSC (Sc3220003) SC3220003South Carolina47,8388.3 ppt4
Newberry Co W&SA (Sc3620002) SC3620002South Carolina11,1578.3 ppt4
Columbia City of (Sc4010001) SC4010001South Carolina354,0688.1 ppt5
West Columbia City of (Sc3210004) SC3210004South Carolina34,0287.7 ppt8
Lexington Town of (3210001) SC3210001South Carolina24,2847.2 ppt4
Saluda Co W&s Authority (4120001) SC4120001South Carolina4,5357.1 ppt4
The Cape Master System NC0465199North Carolina11,5877.0 ppt2
Goose Creek City of (Sc0810004) SC0810004South Carolina43,7441
Bladen Co Wtr Dist-East Bladen NC0309060North Carolina4,3106.8 ppt1
Amicks Ferry Wtr System (Sc3250077) SC3250077South Carolina3,9376.6 ppt4
Big Sandy Water District KY0100944Kentucky13,0446.3 ppt1
Clinton City of (Sc3010002) SC3010002South Carolina8,9384.9 ppt2
Cayce City of (Sc3210003) SC3210003South Carolina17,4604.8 ppt2

Filters and testing

NSF/ANSI 58 (reverse osmosis); carbon filters vary for short-chain PFAS

A standard number by itself is not a contaminant claim. Check the product's current certification listing and performance data sheet for HFPO-DA (GenX) or the specific contaminant you want to reduce. A utility-level record is not a test of your own faucet.

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